학력

• 2013.02

  서울대학교 의과대학 대학원 분자종양의학 박사

• 2006.02

  서울대학교 의과대학 대학원 분자종양의학 석사

• 2001.02

  인제대학교 의과대학 의학과 학사

주요경력

• 2022.03 ~ 현재

  인하대병원 소아청소년과 부교수

• 2021.09 ~ 2022.02

  인하대병원 소아청소년과 임상부교수

• 2016.09 ~ 2021.06

  Memorial Sloan Kettering Cancer Center, Research fellow

• 2012.03 ~ 2017.08

  인제대학교 의과대학 의학과 소아청소년과 조교수

• 2010.03 ~ 2012.02

  인제대학교 의과대학 의학과 소아청소년과 전임강사

• 2009.03 ~ 2010.02

  서울대학교 암연구소 소아청소년과 연구원

• 2008.03 ~ 2009.02

  서울아산병원 소아종양혈액과 임상강사

• 2007.03 ~ 2008.02

  국립암센터 소아암센터 임상강사

• 2006.03 ~ 2007.02

  서울대학교 어린이병원 소아혈액종양 임상강사

• 2002.03 ~ 2006.02

  서울대학교 어린이병원 소아청소년과 전공의

• 2001.03 ~ 2002.02

  서울보훈병원 인턴

학회활동

수상경력

주요 논문 및 저서

• 2021

  Treatment of Diffuse Alveolar Hemorrhage: Controlling Inflammation and Obtaining Rapid and Effective Hemostasis. Park JA. Int J Mol Sci. 2021 Jan 14;22(2):793. doi: 10.3390/ijms22020793.

• 2021

  Potent ex vivo armed T cells using recombinant bispecific antibodies for adoptive immunotherapy with reduced cytokine release. Park JA, Santich BH, Xu H, Lum LG, Cheung NV. J Immunother Cancer. 2021 May;9(5):e002222. doi: 10.1136/jitc-2020-002222.

• 2021

  Modulating Tumor Infiltrating Myeloid Cells to Enhance Bispecific Antibody-driven T cell Infiltration and Anti-tumor Response. Park JA, Wang L, Cheung NK, Journal of Hematology and Oncology, 2021, In press,

• 2021

  A Novel Potent Anti-STEAP1 Bispecific antibody to Redirect T Cells for Cancer Immunotherapy. Park JA, Lin T, Long A, Cheung NK, Journal for ImmunoTherapy of Cancer, 2021, In press

• 2020

  Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies. Santich BH, Park JA, Tran H, Guo HF, Huse M, Cheung NV. Sci Transl Med. 2020 Mar 11;12(534)

• 2020

  Targets and Antibody Formats for Immunotherapy of Neuroblastoma. Park JA, Cheung NV. J Clin Oncol. 2020 Mar 13:JCO1901410.

• 2020

  GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma. Park JA, Cheung NV. J Hematol Oncol. 2020 Dec 10;13(1):172. doi: 10.1186/s13045-020-01012-y.

• 2019

  Molecular diagnosis of hereditary spherocytosis by multi-gene target sequencing in Korea: matching with osmotic fragility test and presence of spherocyte. Choi HS, Choi Q, Kim JA, Im KO, Park SN, Park Y, Shin HY, Kang HJ, Kook H, Kim SY, Kim SJ, Kim I, Kim JY, Kim H, Park KD, Park KB, Park M, Park SK, Park ES, Park JA, Park JE, Park JK, Baek HJ, Seo JH, Shim YJ, Ahn HS, Yoo KH, Yoon HS, Won YW, Lee KS, Lee KC, Lee MJ, Lee SA, Lee JA, Lee JM, Lee JH, Lee JW, Lim YT, Jung HJ, Chueh HW, Choi EJ, Jung HL, Kim JH, Lee DS; Hereditary Hemolytic Anemia Working Party of the Korean Society of Hematology. Orphanet J Rare Dis. 2019 May 23;14(1)

• 2018

  Comparison of survival outcome between donor types or stem cell sources for childhood acute myeloid leukemia after allogenic hematopoietic stem cell transplantation. Shim YJ, Lee JM, Kim HS, Jung N, Lim YT, Yang EJ, Hah JO, Lee YH, Chueh HW, Lim JY, Park ES, Park JA. Pediatr Transplant. 2018 Jun 19:e13249

• 2018

  Treatment outcome of pediatric acute lymphoblastic leukemia in Yeungnam region: Multicenter retrospective study of Study Alliance of Yeungnam Pediatric Hematology-Oncology (SAYPH). Yang EJ, Park KM, Park JA, Lim YT. Pediatr Hematol Oncol. 2018 May;35(4):276-287

• 2017

  ATIC Gene Polymorphism and Histologic Response to Chemotherapy in Pediatric Osteosarcoma. Park JA, Shin HY. J Pediatr Hematol Oncol. 2017 Mar 6.

• 2017

  Limitations and opportunities for immune checkpoint inhibitors in pediatric malignancies. Park JA, Cheung NV. Cancer Treat Rev. 2017 Jul;58:22-33.

• 2016

  Sirolimus for Refractory Autoimmune Hemolytic Anemia after Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report and Literature Review of the Treatment of Post-Transplant Autoimmune Hemolytic Anemia. Park JA, Lee HH, Kwon HS, Baik CR, Song SA, Lee JN. Transfus Med Rev. 2016 Jan;30(1):6-14

• 2016

  Improved Outcome of a Reduced Toxicity-Fludarabine, Cyclophosphamide, plus antithymocyte Globulin Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia: Comparison of 2 Multicenter Prospective Studies. Kang HJ1, Hong KT1, Lee JW1, Park JA11, Park SK12, Ahn HS13; Korean Society of Pediatric Hematology-Oncology. Biol Blood Marrow Transplant. 2016 Aug;22(8):1455-9.

• 2016

  Influence of genetic polymorphisms in the folate pathway on toxicity after high-dose methotrexate treatment in pediatric osteosarcoma. Park JA, Shin HY. Blood Res. 2016 Mar;51(1):50-7.

• 2016

  Diffuse alveolar hemorrhage and recombinant factor VIIa treatment in pediatric patients. Park JA. Korean J Pediatr. 2016 Mar;59(3):105-13.

• 2016

  Toxic megacolon and interstitial pneumonia caused by cytomegalovirus infection in a pediatric patient with acute lymphoblastic leukemia receiving chemotherapy. Kwon H, Lee HH, Paik CR, Lim YJ, Park JA. Blood Res. 2016 Dec;51(4):281-285.

• 2015

  Intrapulmonary recombinant factor VIIa for diffuse alveolar hemorrhage in children. Park JA, Kim BJ. Pediatrics. 2015 Jan;135(1):e216-20.

• 2014

  18F-FDG PET for diagnosis and response assessment for aggressive NK cell leukemia. Park JA. Clin Nucl Med. 2014 Apr;39(4):e281-2.

• 2014

  Clinical features and treatment outcomes of Langerhans cell histiocytosis: a nationwide survey from Korea histiocytosis working party. Kim BE, Koh KN, Suh JK, Im HJ, Song JS, Park JA, Kim SK, Park M, Lim YJ, Lee YH, Seo JJ; Korea Histiocytosis Working Party. J Pediatr Hematol Oncol. 2014 Mar;36(2):125-33

• 2014

  Primary malignant rhabdoid tumor of greater omentum in 10-year-old girl. Nam SH, Park JA, Kim YM. Ann Surg Treat Res. 2014 Jan;86(1):50-3.

• 2014

  Successful rescue of early graft failure in pediatric patients using T-cell-depleted haploidentical hematopoietic SCT. Park JA, Koh KN, Choi ES, Jang S, Kwon SW, Park CJ, Seo JJ, Im HJ. Bone Marrow Transplant. 2014 Feb;49(2):270-5.

• 2013

  Favorable outcome in a child with EBV-negative aggressive NK cell leukemia. Park JA, Jun KR, Nam SH, Ghim TT. Int J Hematol. 2013 May;97(5):673-6.

• 2013

  Safety and effects of prophylactic defibrotide for sinusoidal obstruction syndrome in hematopoietic stem cell transplantation. Park M, Park HJ, Eom HS, Kwon YJ, Park JA, Lim YJ, Yoon JH, Kong SY, Ghim TT, Lee HW, Yun T, Park BK. Ann Transplant. 2013 Jan 28;18:36-42.

• 2012

  6-Thioguanine-Induced Hepatic Sinusoidal Obstruction Syndrome in a Leukemic Child with TPMT Heterozygote. Kwon YJ, Yoon JH, Park JA, Bang JS, Park BK, Choi JI, Kong SY, Park HJ. Clin Pediatr Hematol Oncol. 2012 Oct;19(2):109-113

• 2012

  A novel mutation in the ABCD1 gene of a Korean boy diagnosed with X-linked adrenoleukodystrophy. Jeong A. Park, Kyung Ran Jun b, Sung-Hee Han c, Gu-Hwan Kim d, Han-Wook Yoo d, Yun Jung Hur. Gene 498 (2012) 131–133

• 2011

  Three-way Translocation of MLL/MLLT3, t(1;9;11)(p34.2;p22;q23), in a Pediatric Case of Acute Myeloid Leukemia. Jun KR, Lee JN, Park JA, Kim HR, Shin JH, Oh SH, Lee JY, Song SA. Korean J Lab Med. 2011 Apr;31(2):127-9.

• 2011

  A Case of an Imported Dengue Hemorrhagic Fever with Spontaneous Bleeding: Case Report and Review of the Literature. Choi HH, Park JA, Kim JS, Hur YJ, Song MS, Hwang TG, Choi Y. Korean J Pediatr Infect Dis. 2011 Dec;18(2):207-211 (Korean)

• 2010

  Improved outcome in childhood ALL with intensive consolidation and hematopoietic stem cell transplant. Park JA, Ghim T, Bae KW, Koh KN, Im HJ, Seo JJ. Korean J Hematol. 2010 Jun;45(2):109-14.

• 2010

  Hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation: incidence, risk factors, and outcome. SH Lee1, KH Yoo1, KW Sung1, HH Koo1, YJ Kwon2, MM Kwon2, HJ Park2, B-K Park2, YY Kim3, JA Park, HJ Im4, JJ Seo4, HJ Kang5, HY Shin5 and HS Ahn. Bone Marrow Transplant. 2010 Aug;45(8):1287-93.

• 2010

  Normalization of red cell enolase level following allogeneic bone marrow transplantation in a child with Diamond-Blackfan anemia. Park JA, Lim YJ, Park HJ, Kong SY, Park BK, Ghim TT. J Korean Med Sci. 2010 Apr;25(4):626-9.

• 2009

  Stem cell transplant in the treatment of childhood biphenotypic acute leukemia. Park JA, Ghim TT, Bae K, Im HJ, Jang SS, Park CJ, Chi HS, Seo JJ. Pediatr Blood Cancer. 2009 Sep;53(3):444-52.

• 2009

  Improvement of Induction Remission Rate by Modifying the Dose of Idarubicin for Relapsed Childhood Acute Lymphoblastic Leukemia. Yoon JH, Park JA, Kim EK, Kang HJ, Shin HY, Ahn HS. J Korean Med Sci. 2009 Apr;24(2):281-288.

• 2008

  Unrelated bone marrow transplantation with a reduced toxicity myeloablative conditioning regimen in Wiskott-Aldrich syndrome. Kang HJ, Shin HY, Ko SH, Park JA, Kim EK, Rhim JW, Kim JG, Ahn HS. J Korean Med Sci. 2008 Feb;23(1):146-8.

• 2008

  Acute intestinal pseudo-obstruction after induction treatment of relapsed acute promyelocytic leukemia with arsenic trioxide. Park JA, Yun JH, Kang HJ, Shin HY, Ahn HS. Pediatr Blood Cancer. 2008 Apr;50(4):872-4.

• 2008

  Adenocarcinoma of lung in never smoked children. Park JA, Park HJ, Lee JS, Ha JO, Lee GK, Park BK, Ghim TT. Lung Cancer. 2008 Aug;61(2):266-9.

• 2008

  Initial Response to Treatment was Highly Associated with the Prognosis of Childhood rhabdomyosarcoma: A Retrospective Analysis of a Single Center Experience in Korea. Park JA, Kim EK, Kang HJ, Shin HY, Kim IH, Ahn HS. Cancer Res Treat. 2008 Sep;40(3):111-5.

• 2007

  Retrospective analysis of peripheral blood stem cell transplantation for the treatment of high-risk neuroblastoma. Kim EK, Kang HJ, Park JA, Choi HS, Shin HY, Ahn HS. J Korean Med Sci. 2007 Sep;22 Suppl:S66-72.

• 2006

  Clinical Aspects of Craniofacial Osteosarcoma in Childhood: A Single Institution Experience. Jong Hyung Yoon, M.D., Jeong Ah Park, M.D., Eun Kyung Kim, M.D., Hyoung Jin Kang, M.D., Hee Young Shin, M.D. and Hyo Seop Ahn, M.D Clin Pediatr Hematol Oncol 2006;13:187-98 (Korean)

• 2005

  Intracranial Atypical Teratoid/Rhabdoid Tumor: Retrospective Analysis in a Single Institution. Eun Kyung Kim, M.D., Jeong Ah Park, M.D., Jong Hyung Yoon, M.D., Soo Hyun Lee, M.D., Hyoung Jin Kang, M.D., Hee Young Shin, M.D. and Hyo Seop Ahn, M.D. Korean J Pediatr Hematol Oncol 2005;12:286-94 (Korean)

• 2005

  A Case of Opsoclonus-Myoclonus-Ataxia Syndrome in Ganglioneuroblastoma. Eun Kyung Kim, M.D., Jeong Ah Park, M.D., Eun Sil Park, M.D., Hyoung Soo Choi, M.D., Hee Young Shin, M.D., Hyo Seop Ahn, M.D. and Kwi Won Park, M.D.Korean J Pediatr Hematol Oncol 2005;12:114-9 (Korean)

• 2005

  Establishment of Human Bone Marrow-Derived Mesenchymal Stem Cell Lines with SV40 Large T Antigen and Their Differentiation to Chondrocytes. Park JA, SH Koh, Kim EK, Kang HJ, Shin HY, Ahn HS. Korean J Pediatr Hematol-Oncology 2005 Apr; 12(1):99-107. (Korean)

• 2005

  Polymorphism of matrix metalloproteinase-3 promoter gene as a risk factor for coronary artery lesions in Kawasaki disease. Park JA, Shin KS, Kim YW. J Korean Med Sci. 2005 ;20(4):607-11.