학력

• 2019.02

  성균관대학교 융합의과학과 생물정보학 이학박사

• 2014.02

  성균관대학교 의학과 피부과학 의학석사

• 2009.02

  인하대학교 의학과 의학학사

주요경력

• 2021.01 ~ 현재

  인하대병원 피부과 조교수

• 2020.03 ~ 2020.12

  인하대병원 피부과 임상조교수

• 2019.03 ~ 2020.02

  중앙보훈병원 보훈의학연구소 연구전담의사

• 2014.03 ~ 2019.02

  삼성서울병원 삼성유전체연구소 연구원

• 2010.03 ~ 2014.02

  삼성서울병원 피부과 전공의

• 2009.03 ~ 2010.02

  삼성서울병원 인턴

학회활동

수상경력

주요 논문 및 저서

• 2020

  Evolutionary processes of melanomas from congenital melanocytic nevi. Lim Y, Shin HT, Choi Y, Lee DY. Pigment Cell Melanoma Res. 2020 Mar;33(2):318-325.

• 2019

  Intratumor heterogeneity inferred from targeted deep sequencing as a prognostic indicator. Oh BY, Shin HT, Yun JW, Kim KT, Kim J, Bae JS, Cho YB, Lee WY, Yun SH, Park YA, Park YH, Im YH, Lee J, Joung JG, Kim HC, Park WY. Sci Rep. 2019 Mar 14;9(1):4542.

• 2019

  The concept of nail matrix onychodermis (onychomatricodermis) in the nail unit: Histology and elastin immunohistochemistry. Lee DY, Park JH, Li M, Abudureyimu G, Oh SJ, Shin HT, Jang KT, Kwon GY, Shim JS, Kwon EJ. J Cutan Pathol. 2019 Jul;46(7):490-497.

• 2019

  Junction Location Identifier: Accurate Detection of DNA Fusions in Clinical Sequencing for Precision Oncology. Shin HT, Kim NKD, Yun JW, Lee B, Kyung S, Lee KW, Ryu D, Kim J, Bae JS, Park D, Choi YL, Lee SH, Ahn MJ, Park K, Park WY. J Mol Diagn. 2019 Dec 25. pii: S1525-1578(19)30456-8.

• 2018

  Genomic alterations of ground-glass nodular lung adenocarcinoma. Lee H, Joung JG, Shin HT, Kim DH, Kim Y, Kim H, Kwon OJ, Shim YM, Lee HY, Lee KS, Choi YL, Park WY, Hayes DN, Um SW. Sci Rep. 2018 May 16;8(1):7691.

• 2018

  Integrin β3 Inhibition Enhances the Antitumor Activity of ALK Inhibitor in ALK-Rearranged NSCLC. Noh KW, Sohn I, Song JY, Shin HT, Kim YJ, Jung K, Sung M, Kim M, An S, Han J, Lee SH, Lee MS, Choi YL. Clin Cancer Res. 2018 Sep 1;24(17):4162-4174

• 2018

  Clinical Relevance of Genomic Changes in Recurrent Pediatric Solid Tumors. Lee B, Lee JW, Shim JH, Joung JG, Yun JW, Bae JS, Shin HT, Sung KW, Park WY. Transl Oncol. 2018 Dec;11(6):1390-1397.

• 2017

  Mutational profiling of acral melanomas in Korean populations. Shim JH, Shin HT, Park J, Park JH, Lee JH, Yang JM, Kim DH, Jang KT, Lee DY. Exp Dermatol. 2017 Oct;26(10):883-888.

• 2017

  Characterization of background noise in capture-based targeted sequencing data. Park G, Park JK, Shin SH, Jeon HJ, Kim NKD, Kim YJ, Shin HT, Lee E, Lee KH, Son DS, Park WY, Park D. Genome Biol. 2017 Jul 21;18(1):136.

• 2017

  Molecular breakdown: a comprehensive view of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer. Noh KW, Lee MS, Lee SE, Song JY, Shin HT, Kim YJ, Oh DY, Jung K, Sung M, Kim M, An S, Han J, Shim YM, Zo JI, Kim J, Park WY, Lee SH, Choi YL. J Pathol. 2017 Nov;243(3):307-319.

• 2017

  A Method to Evaluate the Quality of Clinical Gene-Panel Sequencing Data for Single-Nucleotide Variant Detection. Lee C, Bae JS, Ryu GH, Kim NKD, Park D, Chung J, Kyung S, Joung JG, Shin HT, Shin SH, Kim Y, Kim BS, Lee H, Kim KM, Kim JS, Park WY, Son DS. J Mol Diagn. 2017 Sep;19(5):651-658.

• 2017

  Prevalence and detection of low-allele-fraction variants in clinical cancer samples. Shin HT, Choi YL, Yun JW, Kim NKD, Kim SY, Jeon HJ, Nam JY, Lee C, Ryu D, Kim SC, Park K, Lee E, Bae JS, Son DS, Joung JG, Lee J, Kim ST, Ahn MJ, Lee SH, Ahn JS, Lee WY, Oh BY, Park YH, Lee JE, Lee KH, Kim HC, Kim KM, Im YH, Park K, Park PJ, Park WY. Nat Commun. 2017 Nov 9;8(1):1377.

• 2016

  Highly Concordant Key Genetic Alterations in Primary Tumors and Matched Distant Metastases in Differentiated Thyroid Cancer. Sohn SY, Park WY, Shin HT, Bae JS, Ki CS, Oh YL, Kim SW, Chung JH. Thyroid. 2016 May;26(5):672-82.

• 2016

  Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis. Kim SJ, Shin HT, Lee HO, Kim NK, Yun JW, Hwang JH, Kim K, Park WY. Oncotarget. 2016 Oct 18;7(42):68350-68359.

• 2015

  Photodynamic therapy using a new formulation of 5-aminolevulinic acid for wrinkles in Asian skin: A randomized controlled split face study. Shin HT, Kim JH, Shim J, Lee JH, Lee DY, Lee JH, Yang JM. J Dermatolog Treat. 2015 Jun;26(3):246-51.

• 2015

  Identification of Driving ALK Fusion Genes and Genomic Landscape of Medullary Thyroid Cancer. Ji JH, Oh YL, Hong M, Yun JW, Lee HW, Kim D, Ji Y, Kim DH, Park WY, Shin HT, Kim KM, Ahn MJ, Park K, Sun JM. PLoS Genet. 2015 Aug 21;11(8):e1005467.

• 2015

  Role of HER2 mutations in refractory metastatic breast cancers: targeted sequencing results in patients with refractory breast cancer. Park YH, Shin HT, Jung HH, Choi YL, Ahn T, Park K, Lee A, Do IG, Kim JY, Ahn JS, Park WY, Im YH. Oncotarget. 2015 Oct 13;6(31):32027-38.

• 2014

  Histopathological analysis of the progression pattern of subungual melanoma: late tendency of dermal invasion in the nail matrix area. Shin HT, Jang KT, Mun GH, Lee DY, Lee JB. Mod Pathol. 2014 Nov;27(11):1461-7.

• 2014

  Relative high interest in acne on the internet: a web-based comparison using google trends. Shin HT, Park SW, Lee DY. Ann Dermatol. 2014 Oct;26(5):641-2.

• 2013

  The presence of onychodermis in magnetic resonance imaging of the nail unit: correlation with histopathology. Park JH, Shin HT, Lee DY, Shim JS, Choi SH, Lee JH. J Cutan Pathol. 2013 May;40(5):519-20.

• 2013

  Nuclear and cytoplasmic localization of β-catenin in the nail-matrix cells and in an onychomatricoma. Kim CR, Shin HT, Park JH, Lee DY, Yang JM, Kwon GY, Jang KT, Lee KH, Shim JS. Clin Exp Dermatol. 2013 Dec;38(8):917-20.

• 2012

  Onychodermis (specialized nail mesenchyme) containing onychofibroblasts in horizontal sections of the nail unit. Lee DY, Park JH, Shin HT, Jang KT, Kwon GY, Shim JS. Br J Dermatol. 2012 May;166(5):1127-9.

• 2012

  The presence and localization of onychodermis (specialized nail mesenchyme) containing onychofibroblasts in the nail unit: a morphological and immunohistochemical study. Lee DY, Park JH, Shin HT, Yang JM, Jang KT, Kwon GY, Lee KH, Shim JS. Histopathology. 2012 Jul;61(1):123-30.

• 2012

  Immunohistochemical study of epithelial markers in longitudinal and transverse sections of the human nail unit. Lee DY, Park JH, Shin HT, Jang KT, Shim JS. Clin Exp Dermatol. 2012 Aug;37(6):688-9.

• 2012

  World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphoma in Korea: a retrospective study at a single tertiary institution. Park JH, Shin HT, Lee DY, Lee JH, Yang JM, Jang KT, Ko YH. J Am Acad Dermatol. 2012 Dec;67(6):1200-9.

• 2011

  A novel method to differentiate the epidermal side from the dermal side in suction-blistered epidermal grafting. Lee DY, Shin HT. Dermatol Surg. 2011 Jul;37(7):1066-7.