Inha University Hospital is the first hospital in Asia to install the 4th generation and 4-dimensional Robotic Cyber Knife Radiosurgery system for treatment of various cancers and lesions in the body and central nervous system, many of which have been diagnosed as inoperable, unresectable and oligo-metastatic disease. Cyber Knife radiosurgery system delivers hundreds of finely collimated radiation beam to the tumor and effectively eradicats tumor cells without pain, bleeding and anesthesia. With Synchrony system installation, patients no longer have to hold their breath during a procedure because it simultaneously tracks both the movement of the tumor and breathing patterns of the patient and treatment complications are reduced. The Cyber Knife, a robotic radiosurgery system, has very many advantages that is no recovery time, simple outpatient treatment process, extremely accurate radiation targeting, higher doses of radiation can be used, minimizing damage to healthy tissue, and immediately resume normal daily activities, compared to Gamma knife radiosurgery as well as conventional radiation therapy such as tomo therapy and image guided radiation therapy. Cyber Knife gives new hope for the treatment of tumors and lesions that previously have been diagnosed as inoperable or untreatable with existing technology.